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刘昕晔

发布时间：2018-09-14

刘昕晔

博士

副教授，硕士研究生导师

联系电话：17332926183

电子邮件：xinyeliu@hebtu.edu.cn

所属专业：细胞生物学

学习工作经历

2018年7月至今，河北师范大学，副教授

2011年9月至2018年6月，中国农业大学，博士研究生毕业，获得农学博士学位

2013年11月至2014年4月，美国亚利桑那大学，农业与生命科学学院，访问学生

2007年9月至2011年7月，河北农业大学，本科毕业，获得农学学士学位

主要教学科研工作

本人主要的研究内容是以多组学高通量数据分析为切入点，解析重要生物学问题背后的分子调控机制和分子调控网络，重点关注小麦种子形成、储存和萌发过程中的调控网络解析。目前，本人的研究工作围绕长链非编码RNA（long non-coding RNA）展开。近些年来，越来越多的研究表明长链非编码RNA具有重要的物学功能：长链非编码RNA可引起作物驯化过程中伴随的表型变异，可调控重要农艺性状，影响植物对环境因素的应答过程，并参与多种植物生长发育过程。本人的研究通过全基因组水平的鉴定、转基因遗传材料的创制，以及分子机制解析，系统阐述长链非编RNA相关调控网络在小麦种子萌发过程中的生物学功能。

本人主讲《现代生物技术（双语）》、《分子生物学实验》、《基因组学（双语）》和《中学生物实验教学》等本科生课程，以及承担研究生课程《分子细胞生物学大实验》部分内容。

承担的科研项目

1、小麦长链非编码RNA 159eTM与miR159a互作调控种子萌发的分子机制研究，32201816，国家自然科学青年基金，2023年1月-2025年12月。

2、长链非编码RNA SUR1调控小麦萌发期耐盐性的分子机制研究，BJK2024019，河北省自然科学基金青年拔尖人才项目，2024年1月-2026年12月。

3、小麦种子萌发相关长链非编码RNA的鉴定及功能分析，C2020205006，河北省自然科学基金青年项目，2020年1月-2022年12月。

4、基于高通量测序技术对小麦种子萌发相关长链非编码RNA的挖掘，QN2020184，河北省教育厅青年项目，2020年1月-2022年12月。

5、小麦全基因组水平环形RNA的鉴定，L2019B20，河北师范大学博士（后）基金，2019年1月-2021年12月。

6、“四新建设”背景下基于OBE理念的《现代生物技术》教学内容的“两性一度”设计，2023XJJG003，河北师范大学教学改革研究与实践校级重点项目，2023年7月-2025年7月。

发表的论文（#表示共同第一作者）

入职河北师范大学后参与发表的论文：

1．Li Bingjie#, Jiang Shimeng#, Gao Liang#, Wang Wenhui, Luo Haozheng, Dong Yining, Gao Zhihua, Zheng Shuzhi, Liu Xinye*, Tang Wenqiang* （2024） Heat Shock Factor A1s are required for phytochrome-interacting factor 4-mediated thermomorphogenesis in Arabidopsis. Journal of Integrative Plant Biology 66(1): 20-35.（IF=11.4）

2．Niu Yanxiao#, Bai Jiaoteng#, Liu Xinye#, Zhang Hao#, Bao Jingpei, Zhao Weishuang, Hou Yifeng, Deng Xian,Yang Chao, Guo Lin, Geng Ziyue, Xie Honglian, Wu Hongyuan, Shen Meng, Lou Xiaojie, Tang Wenqiang, Liu Xigang, Sun Daye, Cao Xiaofeng, Zheng Shuzhi*（2022） HISTONE DEACETYLASE 9 transduces heat signal in plant cells. Proc Natl Acad Sci USA 119 (45) e2206846119.（IF=12.779）

3．Liu Yuliang#, Liu Xinye#, Wang Xue, Gao Kang, Qi Weiwei, Ren Huimin, Hu Haorui, Sun Daye, Bai Jiaoteng*, Zheng Shuzhi* (2020) Heterologous expression of heat stressresponsive AtPLC9 confers heat tolerance in transgenic rice. BMC plant Biology 20(1):514.（IF=3.497）

4．Lin Wei, Wang Yuehua, Liu Xinye, Shang Jianxiu*, Zhao Liqun* (2021) OsWAK112, A Wall-Associated Kinase, Negatively Regulates Salt Stress Responses by Inhibiting Ethylene Production. Frontiers in Plant Science 12(7):751956.（IF=6.627）

5．Li Yinghui, Qiu Lina, Liu Xinye, Zhang Qiang, Zhuansun Xiangxi, Fahima Tzion, Krugman Tamar, Sun Qixin, Xie Chaojie (2020) Glycerol-Induced Powdery Mildew Resistance in Wheat by Regulating Plant Fatty Acid Metabolism, Plant Hormones Cross-Talk, and Pathogenesis-Related Genes. International Journal of Molecular Sciences 21(2): 673.（IF=4.556）

6．Zheng Shuzhi, Hu Hongmiao, Ren Huimin, Yang Zhenlin, Qiu Qi, Qi Weiwei, Liu Xinye, Chen Xiaomei, Cui Xiekui, Li Sisi, Zhou Bing, Sun Daye, Cao Xiaofeng, Du Jiamu (2019) The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor. Nature Communications 10: 1303.（IF=12.121）

7．Chen LianGe, Gao Zhihua, Zhao Zhiying, Liu Xinye, Li Yongpeng, Zhang, Yuxiang, Liu Xigang, Sun Yu, Tang Wenqiang (2019) BZR1 Family Transcription Factors Function Redundantly and Indispensably in BR Signaling but Exhibit BRI1-Independent Function in Regulating Anther Development in Arabidopsis. Molecular Plant 12(10): 1408-1415.（IF=12.084）

8．Li Bingjie, Gao Zhihua, Liu Xinye, Sun Daye, Tang Wenqiang (2019) Transcriptional Profiling Reveals a Time-of-Day-Specific Role of REVEILLE 4/8 in Regulating the First Wave of Heat Shock-Induced Gene Expression in Arabidopsis. Plant Cell 31(10): 2353-2369.（IF=9.618）

9．Wang Lishuan, Wang Chunlei, Liu Xinye, Cheng Jinkui, Li Shaofang, Zhu Jian Kang, Gong Zhizhong (2019) Peroxisomal beta-oxidation regulates histone acetylation and DNA methylation in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 116(21): 10576-10585.（IF=9.412）

攻读博士学位期间参与发表的论文：

1．Guo Guanghui#, Liu Xinye#, Sun Fenglong, Cao Jie, Huo Na, Wuda Bala, Xin Mingming, Hu Zhaorong, Du Jinkun, Xia Rui, Rossi Vincenzo, Peng Huiru, Ni Zhongfu, Sun Qixin, Yao Yingyin (2018). Wheat miR9678 Affects Seed Germination by Generating Phased siRNAs and Modulating Abscisic Acid/Gibberellin Signaling. Plant Cell 30(4): 796-814.（IF=9.618）

2．Zhang Liyuan#, Liu Xinye#, Gaikwad Kishor, Kou Xiaoxia, Wang Fei, Tian Xuejun, Xin Mingming, Ni Zhongfu, Sun Qixin, Peng Huiru, Vierling Elizabeth (2017) Mutations in eIF5B Confer Thermosensitive and Pleiotropic Phenotypes via Translation Defects in Arabidopsis thaliana. Plant Cell 29(8): 1952-1969.（IF=9.618）

3．Yang Hua#, Liu Xinye#, Xin Mingming, Du Jinkun, Hu Zhaorong, Peng Huiru, Rossi Vincenzo, Sun Qixin, Ni Zhongfu, Yao Yingyin (2016) Genome-Wide Mapping of Targets of Maize Histone Deacetylase HDA101 Reveals Its Function and Regulatory Mechanism during Seed Development. Plant Cell 28(3): 629-645.（IF=9.618）

4．Liu Kaiye, Cao Jie, Yu Kuohai, Liu Xinye, Gao Yujiao, Chen Qian, Zhang Wenjia, Peng Huiru, Du Jinkun, Xin Mingming, Hu Zhaorong, Guo Weilong, Rossi Vincenzo, Ni Zhongfu, Sun Qixin, Yao Yingyin (2019) Wheat TaSPL8 Modulates Leaf Angle Through Auxin and Brassinosteroid Signaling. Plant Physiology 181(1): 179-194.（IF=6.902）

5．Mei Zheng, Xingbei Liu, Jingchen Lin, Xinye Liu, Zhouying Wang, Mingming Xin, Yingyin Yao, Huiru Peng, Dao Xiu Zhou, Zhongfu Ni, Qixin Sun, Zhaorong Hu (2019)  Histone acetyltransferase GCN5 contributes to cell wall integrity and salt stress tolerance by altering expression of cellulose synthesis genes. Plant Journal 97(3): 587-602.（IF=6.141）

6．Cao Jie, Zsolt Gulyás, Balázs Kalapos, Ákos Boldizsár, Liu Xinye, Magda Pál, Yao Yingying, Gábor Galiba, Gábor Kocsy (2019) Identification of a redox-dependent regulatory network of miRNAs and their targets in wheat. Journal of Experimental Botany 70(1): 85-99.（IF=5.908）

7．Zhang Ning, Xu Jing, Liu Xinye, Liang Wenxing, Xin Mingming, Du Jinkun, Hu Zhaorong, Peng Huiru, Guo Weilong, Ni Zhongfu, Sun Qixin, Yao Yingyin (2019)  Identification of HSP90C as a substrate of E3 ligase TaSAP5 through ubiquitylome profiling. Plant Science 287: 110170.（IF=3.591）

8．Wang Tianya, Xing Jiewen, Liu Xinye, Yao Yingyin, Hu Zhaorong, Peng Huiru, Xin Mingming, Zhou Dao Xiu, Zhang Yirong, Ni Zhongfu (2018) GCN5 contributes to stem cuticular wax biosynthesis by histone acetylation of CER3 in Arabidopsis. Journal of Experimental Botany 69(12): 2911-2922.（IF=5.908）

9．Zhai Huijie, Feng Zhiyu, Du Xiaofen, Song Yane, Liu Xinye, Qi Zhongqi, Song Long, Li Jiang, Li Linghong, Peng Huiru, Hu Zhaorong, Yao Yingyin, Xin Mingming, Xiao Shihe, Sun Qixin, Ni Zhongfu (2018) A novel allele of TaGW2-A1 is located in a finely mapped QTL that increases grain weight but decreases grain number in wheat (Triticum aestivum L.). Theoretical and Applied Genetics 131(3): 539-553.（IF=4.439）

10．Zhang Ning, Yin Yujing, Liu Xinye, Tong Shaoming, Xing Jiewen, Zhang Yuan, Pudake Ramesh N., Miranda Izquierdo Edenys, Peng Huiru, Xin Mingming, Hu Zhaorong, Ni Zhongfu, Sun Qixin, Yao Yingyin (2017) The E3 Ligase TaSAP5 Alters Drought Stress Responses by Promoting the Degradation of DRIP Proteins. Plant Physiology 175(4): 1878-1892.（IF=6.902）

11．Wang Tianya, Xing Jiewen, Liu Xinye, Liu Zhenshan, Yao Yingyin, Hu Zhaorong, Peng Huiru, Xin Mingming, Zhou Dao Xiu, Zhang Yirong, Ni Zhongfu (2016) Histone acetyltransferase general control non-repressed protein 5 (GCN5) affects the fatty acid composition of Arabidopsis thaliana seeds by acetylating fatty acid desaturase3 (FAD3). Plant Journal 88(5): 794-808.（IF=6.141）

12．Li Yangyang, Wang Cheng, Liu Xinye, Song Jian, Li Hongjian, Sui Zhipeng, Zhang Ming, Fang Shuang, Chu Jinfang, Xin Mingming, Xie Chaojie, Zhang Yirong, Sun Qixin, Ni Zhongfu (2016) Up-regulating the abscisic acid inactivation gene ZmABA8ox1b contributes to seed germination heterosis by promoting cell expansion. Journal of Experimental Botany 67(9): 2889-2900.（IF=5.908）

13．Zhai Huijie, Feng Zhiyu, Li Jiang, Liu Xinye, Xiao Shihe, Ni Zhongfu, Sun Qixin (2016) QTL Analysis of Spike Morphological Traits and Plant Height in Winter Wheat (Triticum aestivum L.) Using a High-Density SNP and SSR-Based Linkage Map, Frontiers in Plant Science, 2016, 7: 1617.（IF=4.402）

14．Wang Tianya, Sui Zhipeng, Liu Xinye, Li Yangyang, Li Hongjian, Xing Jiewen, Song Fangwei, Zhang Yirong, Sun Qixin, Ni Zhongfu (2016) Ectopic expression of a maize hybrid up-regulated gene, ErbB-3 binding Protein 1 (ZmEBP1), increases organ size by promoting cell proliferation in Arabidopsis. Plant Science 243: 23-34.（IF=3.591）

教学科研奖励

第三批全国党建工作样板支部培育单位负责人 2022年

河北省“冀青之星”称号 2021年

石家庄市“实干兴石”青年称号 2023年

河北师范大学“青年五四”奖章 2023年

河北师范大学优秀业务班主任 2021年

河北师范大学本科教学质量优秀教师 2022年

任职情况

河北师范大学生命科学学院细胞生物学党支部书记